Given we've managed to almost double CO2 levels in the earth's atmosphere, I am waiting for someone to draw a rectangle in Web Mercator around the entire earth, and tag it **man_made=air**... ;-)
No, seriously, please stick to conventional tagging practices and use your editor's presets. Keys and tags are just a way to classify something, the exact names are only of secondary importance. Even if a key may not feel "natural", please still use it if it is the documented key for the feature.
In your case:
- **natural=water**
- **leisure=marina**
would be a good start.
This way, consumers and renderers of the data, don't have to check every possible exotic alternative tag.
Last remark, in this specific case, the fact that it is "man made" is already reflected in the **leisure=marina** tag. Marinas are by definition man made, even if just marked out by buoys instead of dug, so no need for additional tags.