Trying to figure out if a point is to north/south/east or west of a single dropoff location

While solving a routing problem I need to figure out if certain points lay to N, S, E ,W of a given drop off location. Is there any python based solution available for this? My approach is to handle goods coming from each direction separately. e.g if 5 points lie to North of final destination I will try to find an optimized path between those points and the drop off. But couldn't figure out how to calculate/get this info I am using OSRM for route calculation.